Researchers reveal unprecedented insights into insulin resistance that could pave the way for better treatments and earlier detection of type 2 diabetes.
A specific group of nerve cells in the brain stem appears to control how semaglutide affects appetite and weight — without causing nausea.
In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists have now derived universal rules to enable the de novo design of optimal enzymes. As an example, they considered the enzymatic reaction of breaking a dimer …
Scientists create a floss pick that samples cortisol within saliva as a marker of stress and quantifies it with a built-in electrode. The system uses a polymer casting technology that can be adapted to capture a wide a range of markers, such as estroge…
Daylight can boost the immune system’s ability to fight infections.
Some patients with a rare form of ALS benefited from an experimental therapy, with biomarker evidence of reduced injury to neurons and even limited functional recovery.
Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies.
For the nearly 30 percent of major depressive disorder patients who are resistant to treatment, ketamine provides some amount of normalcy, but it requires frequent treatment and can have side effects. Researchers now show in proof-of-concept experiment…
Scientists have developed new tools to improve gene therapy in advanced stages of inherited retinal diseases (IRDs) such as retinitis pigmentosa and Leber congenital amaurosis.
For gene therapy to work well, therapeutic molecules need to be efficiently delivered to the correct locations in the body — a job commonly given to adeno-associated viruses (AAV). To improve the AAV’s ability to deliver therapeutics specifically to t…
